Ophthalmic Pathology by Thomas J. Cummings

Author:Thomas J. Cummings
Language: eng
Format: epub
Publisher: Springer New York, New York, NY

Fig. 5.29Congenital choroidal melanoma showing pigmented, nested, and epithelioid histology

The liver is the most common site of metastasis (Fig. 5.30).

Fig. 5.30Partial hepatic resection showing metastatic choroidal melanoma

A significant percentage of uveal melanomas are nonreactive for an S-100 protein immunohistochemical stain.

Uveal Melanoma Differential Diagnosis

Nevus

Melanocytoma (magnocellular nevus): Melanocytomas are typically encountered in the uveal tract (Fig. 5.31) and optic nerve head.

Fig. 5.31Clinical image of the left eye with a melanocytoma of the iris at approximately 8:00–9:00

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